Use of dopamine D3 receptor ligands for the production of drugs for treating renal function disorders
AssigneeAbbVie Deutschland GmbH & Co. KG
InventorsBernd Mühlbauer, Gerhard Groβ, Dorothea Starck, Hans-Jörg Treiber
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Abstract
The invention relates to the use of dopamine D3 receptor ligands for the production of drugs for treating renal function disorders.
Claims25
A method for the treatment of a renal function disorder comprising administering an effective amount of dopamine D3 receptor antagonists to a patient in need thereof, wherein the renal function disorder is selected from the group consisting of
- renal function disorders with glomerular hyperfiltration,
- renal function disorders caused by diabetes mellitus,
- renal function disorders caused by nonrenal hypertension,
- renal function disorders caused by glomerulonephritis,
- renal function disorders caused by ascending urinary tract infections,
- renal function disorders caused by sickle cell anemia,
- renal function disorders caused by compensatory hypertrophy after unilateral nephrectomy, and
- renal function disorders caused by mesangial dysfunction.
A method for the treatment of a renal function disorder associated with glomerular hyperfiltration in a patient which comprises administering to said patient an effective amount of a dopamine D3 receptor antagonist.
A method for the treatment of a renal function disorder associated with albuminurea in a patient which comprises administering to said patient an effective amount of a dopamine D3 receptor antagonist.
A method for the treatment of a renal function disorder associated with glomerular hypertrophy in a patient which comprises administering to said patient an effective amount of a dopamine D3 receptor antagonist.
A method for the treatment of diabetic nephropathy comprising administering an effective amount of dopamine D3 receptor antagonists to a patient in need thereof.
Dependencies are inferred from the claim text.