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US 8,785,446 B2Granted
Treating post-seizure patients
AssigneeChildren's Medical Center Corporation
InventorsFrances E. Jensen, Sanjay N. Rakhade
Life of this patent
Estimating the term…
Abstract
Patients are subject to a post-seizure treatment regime to separately inhibitor consecutive targets of an epileptogenic cascade comprising neurotransmitter receptor signaling, kinase/phosphatase activity, protein translation, and apoptosis or inflammation.
Claims4
A therapeutic method for treating a patient post-seizure comprising administering to the patient NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline-2,3-dione), KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazine), and rapamycin.
Dependencies are inferred from the claim text.