7-phenoxychroman carboxylic acid derivatives

A compound of general formula (I)

• or a pharmaceutically acceptable salt thereof, wherein:
• A is H, CN, Cl, F, cyclopropyl, (1-4 C)alkyl or OMe;
• A1 is H, Cl, Br, F, cyclopropyl, (1-4 C)alkyl or OMe;
• R1 is —W-L1-hetAr1;
• W is —CONR3a— or —NR3bCO—;
• R3a and R3b are each H or methyl;
• L1 is a —(CRaRb)n— or
• n is 0 or 2;
• Ra and Rb are independently H, F, methyl, or cyclopropyl, or
• Ra and Rb together with the carbon to which they are attached form a cyclopropyl ring;
• hetAr1 is heteroaryl ring having the structure:
• wherein m is 0 or 1 and said heteroaryl ring is optionally substituted with one or more Rc substituents,
• zero or one of D4, D5 and D6 is N, the remainder being CH;
• each Rc is independently selected from halogen, CF3, (1-6C)alkyl, —O(1-6C alkyl), cyclopropyl, —O—(CH2CH2)OMe, —S(1-6C alkyl), di(1-6C alkyl)amino, and a 5-6 membered azacycle;
• Ar is phenyl optionally substituted with one or more Rd substituents;
• each Rd is independently selected from (1-6C)alkyl, —O(1-6C)alkyl, halogen, —S(1-6C alkyl), and CF3,
• or two adjacent Rd substituents together with the atoms to which they are attached form a 5-6 membered oxacyclic ring;
• R7a, R7b and R8 are independently H or methyl;
• and
• R10 is H, Me or NH2.