2,5,7-substituted oxazolopyrimidine derivatives

A compound of the formula I,

• wherein
• A is O;
• R1 is selected from (C1-C6)-alkyl;
• R2 is selected from phenyl and pryidinyl, wherein the ring nitrogen atom of the pyridinyl can carry an oxy substituent, and wherein the phenyl and pyridinyl are optionally substituted on one or more ring carbon atoms by identical or different substituents R22;
• R3 is selected from (C3-C7)-cycloalkyl-CuH2u— and Het-CvH2v—, wherein u and v are selected from 1 and 2, or R3 is a residue of a saturated or unsaturated, 3-membered to 10-membered, monocyclic or bicyclic ring which comprises 0, 1, 2, 3 or 4 identical or different ring heteroatoms selected from N,O and S, wherein one or two of the ring nitrogen atoms can carry a hydrogen atom or a (C1-C4)-alkyl substituent and one or two of the ring sulfur atoms can carry one or two oxo groups, and wherein the residue of a ring is optionally substituted on one or more ring carbon atoms by identical or different substituents R31;
• R22 is selected from halogen, hydroxy, (C1-C4)-alkyl-, (C1-C4)-alkyloxy, and oxy;
• R31 is selected from halogen, (C1-C4)-alkyl, (C3-C7)-cycloalkyl, hydroxy, (C1-C4)-alkyloxy, oxo, (C1-C4)-alkyl-S(O)m—, amino, (C-C4)-alkylamino, di((C1-C4)-alkyl)amino, (C1-C4)-alkylcarbonylamino, (C1-C4)-alkylsulfonylamino, nitro, cyano, (C1-C4)-alkylcarbonyl, aminosulfonyl, (C1-C4)-alkylaminosulfonyl and di((C1-C4)-alkyl)aminosulfonyl;
• Het is a residue of a saturated, 4-membered to 7-membered, monocyclic heterocycle which comprises 1 or 2 identical or different ring heteroatoms selected from N, O and S and which is bonded via a ring carbon atom, wherein the residue of a heterocycle is optionally substituted by one or more identical or different substituents selected from fluorine and (C1-C4)-alkyl;
• m is selected from 0, 1 and 2, wherein all numbers m are independent of each other;
• wherein all cycloalkyl groups, independently of each other and independently of any other substituents, are optionally substituted by one or more identical or different substituents selected from fluorine and (C1-C4)-alkyl;
• and
• wherein all alkyl, CuH2u, and CvH2v, groups, independently of each other and independently of any other substituents, are optionally substituted by one or more fluorine substituents,
• or a pharmaceutically acceptable salt thereof.