Compounds for treating cancer and other diseases

A method for inhibiting cancer cell growth, inhibiting cancer cell invasion, inhibiting cancer cell metastasis, modulating cancer cell adhesion, or modulating cancer cell attachment, wherein the cancer is selected from the group of breast cancer, liver cancer, ovarian cancer, bladder cancer, prostatic cancer, skin cancer, bone cancer, brain cancer, leukemia cancer, lung cancer, colon cancer, melanoma cancer, cervical cancer, kidney cancer, pancreatic cancer, and mouth cancer, comprising contacting said cancer cell in a cell culture with an effective amount of compound, wherein the compound is selected from the structure:

• wherein R10 is selected from the group of CH2O-angeloyl, CH2O-tigloyl, CH2O-senecioyl, CH2O-crotonoyl, CH2O-3,3-dimethylartyloyl, CH2O-cinnamoyl, CH2O-pentenoyl, CH2O-hexanoyl, CH2O-benzoyl, CH2O-ethylbutyryl;
• wherein R1, R2, R4, R5, R8, are independently selected from the group of CH2OH, hydroxyl, O-angeloyl, O-tigloyl, O-senecioyl, O-acetyl, O-crotonoyl, O-3,3-dimethylartyloyl, O-cinnamoyl, O-pentenoyl, O-hexanoyl, O-benzoyl, O-ethylbutyryl, O-benzoyl, CH2O-angeloyl, CH2O-tigloyl, CH2O-senecioyl, CH2O-crotonoyl, CH2O-3,3-dimethylartyloyl, CH2O-cinnamoyl, CH2O-pentenoyl, CH2O-hexanoyl, CH2O-benzoyl, and CH2O-ethylbutyryl;
• R3 is H or OH;
• R9, R11, R12, R13, R14 and R15 are CH3;
• and
• R16 is H or R4 and R16 may together form —CH2-X—, CH(OH)—X— or C(═O)—X—, wherein the —X— may be O or NH or S.

A method for inhibiting cancer cell growth, inhibiting cancer cell invasion, inhibiting cancer cell metastasis, modulating cancer cell adhesion, or modulating cancer cell attachment, wherein the cancer is selected from the group of breast cancer, liver cancer, ovarian cancer, bladder cancer, prostatic cancer, skin cancer, bone cancer, brain cancer, leukemia cancer, lung cancer, colon cancer, melanoma cancer, cervical cancer, kidney cancer, pancreatic cancer, and mouth cancer, comprising contacting said cancer cell in vitro with an effective amount of compound selected from the structure:

• wherein R10 is selected from the group of CH2O-angeloyl, CH2O-tigloyl, CH2O-senecioyl, CH2O-crotonoyl, CH2O-3,3-dimethylartyloyl, CH2O-cinnamoyl, CH2O-pentenoyl, CH2O-hexanoyl, CH2O-benzoyl, CH2O-ethylbutyryl;
• wherein R1, R2, R4, R5, R8, are independently selected from the group of CH2OH, hydroxyl, O-angeloyl, O-tigloyl, O-senecioyl, O-acetyl, O-crotonoyl, O-3,3-dimethylartyloyl, O-cinnamoyl, O-pentenoyl, O-hexanoyl, O-benzoyl, O-ethylbutyryl, O-benzoyl, CH2O-angeloyl, CH2O-tigloyl, CH2O-senecioyl, CH2O-crotonoyl, CH2O-3,3-dimethylartyloyl, CH2O-cinnamoyl, CH2O-pentenoyl, CH2O-hexanoyl, CH2O-benzoyl, and CH2O-ethylbutyryl;
• R3 is H or OH;
• and R9, R11, R12, R13, R14 and R15 are CH3.