Compositions and assays for treatment and diagnosis of helicobacter pylori infection and conditions
AssigneeAcademia Sinica
InventorsChun-Hung Lin, Ta-Wei Liu
Life of this patent
Estimating the term…
Abstract
Methods of diagnosing Helicobacter pylori infection or associated conditions are based in part on the correlation of the presence of a α-L-fucosidase 2 marker with the infection. Methods and compositions for treating or preventing Helicobacter pylori infection or associated conditions are based in part on administering an α-L-fucosidase 2 inhibitor to an infected subject or a subject at risk of developing the infection.
Claims5
A method of inhibiting or arresting development of an infection caused by a Helicobacter pylori strain, the method comprising:
- administering to a subject in need thereof a pharmaceutical composition comprising a therapeutically effective amount of an α-L-fucosidase 2 inhibitor, and
- a pharmaceutically acceptable carrier, excipient or diluent;
- wherein
- the Helicobacter pylori strain is resistant to Amoxicillin, Clarithromycin or Levofloxacin.
A method of inhibiting or arresting developing of an infection caused by a Helicobacter pylori strain, the method comprising:
- selecting a subject infected with or suspected of being infected with a Helicobacter pylori strain that is resistant to Amoxicillin, Clarithromycin or Levofloxacin;
- and
- administering to the subject a therapeutically effective amount of an α-L-fucosidase 2 inhibitor.
Dependencies are inferred from the claim text.