Neuregulin based methods and compositions for treating cardiovascular disease
AssigneeZensun (Shanghai) Science & Technology, Co., Ltd.
InventorMingdong Zhou
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Abstract
The present invention relates to compositions and methods for preventing, treating or delaying various cardiovascular diseases or disorders in mammals, particularly in humans. More particularly, the present invention provides for compositions and methods for preventing, treating or delaying various cardiovascular diseases or disorders using, inter alia, a neuregulin protein, or a functional fragment thereof, or a nucleic acid encoding a neuregulin protein, or a functional fragment thereof, or an agent that enhances production and/or function of said neuregulin.
Claims49
A method for treating myocardial infarction or heart failure caused by myocardial infarction in a mammal, comprising administering to a mammal in need thereof a neuregulin 1 protein in an amount from about 10 U/kg to about 400 U/kg of body weight of the mammal once a day.
Dependencies are inferred from the claim text.