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US 8,785,381 B2Granted
Oral GLP-1 formulations
AssigneeEmisphere Technologies, Inc.
InventorDonald J. Sarubbi
Life of this patent
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Abstract
The present invention provides pharmaceutical compositions comprising of at least one delivery agent and GLP-1. These pharmaceutical compositions facilitate the oral delivery of GLP-1, providing improved (e.g. increased) bioavailability of GLP-1 compared to administration of GLP-1 without a delivery agent.
Claims6
A formulation comprising (i) a glucagon-like 1 peptide (GLP-1) compound having the amino acid sequence of SEQ ID NO:
- 2 and (ii) a delivery agent selected from the group consisting of
- and pharmaceutically acceptable salts thereof.
Dependencies are inferred from the claim text.