Method and probe set for detecting cancer
AssigneesMayo Foundation for Medical Education and Research, Abbott Molecular Inc.
InventorsKevin C. Halling, Robert B. Jenkins, Walter King, Irina A. Sokolova, Steven A. Seelig
Life of this patent
Estimating the term…
Abstract
Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
Claims14
A method of detecting aneusomic cells, said method comprising:
- a) obtaining a kit comprising a set of chromosomal probes consisting of centromeric chromosomal probes to chromosomes 3, 7, and 17 or centromeric chromosomal probes to chromosomes 3, 7, and 17 and a locus-specific probe to 9p21;
- b) hybridizing said set of chromosomal probes of said kit to a biological sample from a subject;
- and
- c) detecting aneusomic cells by examining the hybridization pattern of said set of chromosomal probes in said biological sample.
A method of performing fluorescence in situ hybridization, said method comprising:
- a) hybridizing a set of chromosomal probes consisting of centromeric probes to chromosomes 3, 7, and 17 to a biological sample from a subject;
- and
- b) detecting aneusomic cells by examining the hybridization pattern of said set of chromosomal probes in said biological sample.
Dependencies are inferred from the claim text.