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US 8,784,887 B2Granted
Pharmaceutical preparation of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide
AssigneeAiCuris GmbH & Co. KG
InventorsTobias Laich, Katrin Liebelt
Life of this patent
Estimating the term…
Abstract
The invention relates to a pharmaceutical preparation for oral administration comprising N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide or its hydrates and/or solvates, as well as an acid, a method for its production as well as the use of this preparation for the treatment and/or prophylaxis of diseases which are caused by herpes viruses, in particular diseases which are caused by herpes simplex viruses.
Claims17
A pharmaceutical preparation for oral application comprising
- N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide or a hydrate thereof,
- optionally one or more dry binders,
- at least one disintegration auxiliary,
- at least one lubricant and
- optionally a tenside,
- said preparation comprising methanesulfonic acid which is used in a stoichiometric ratio of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide or said hydrate to acid of 1 to 0.10 to 1.10 whereby said acetamide and said acid form a salt.
3 more elements
A compound selected from the group consisting of:
- N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate, and its hydrates.
Dependencies are inferred from the claim text.