Ehrlichia ewingii proteins, nucleic acids, and methods of their use
AssigneeThe Ohio State University Research Foundation
InventorYasuko Rikihisa
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Abstract
The novel omp-1 gene cluster encoding twenty one Ehrlichia ewingii (EE) proteins was isolated and sequenced completely. This invention relates to isolated E. ewingii (EE) polypeptides, isolated polynucleotides encoding EE polypeptides, probes, primers, isolated antibodies and methods of their production, immunogenic compositions and vaccines, as well as methods of using the EE polypeptides, antibodies, probes, and primers for the purpose of diagnosis, therapy and production of vaccines against E. ewingii.
Claims16
An isolated OMP-1-14 E. ewingii polypeptide consisting of a sequence that is at least 85% identical to amino acids 26 to 285 of SEQ ID NO:
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Dependencies are inferred from the claim text.