Method for treating chronic wounds with an extracellular polymeric substance solvating system
AssigneeMedtronic Xomed, Inc.
InventorsMatthew F. Myntti, Dana A. Oliver, James B. Hissong, Jennifer G. Medina
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Abstract
Chronic wounds may be treated by debriding necrotic and other devitalized tissue from the wound, and applying to the wound an extracellular polymeric substance solvating system comprising a metal ion sequestering agent, surfactant and buffering agent. The solvating system disrupts biofilms which may be present in the wound and aids or enables the resumption of normal healing.
Claims26
A method for treating chronic wounds, which method comprises:
- a) debriding at least some necrotic or other devitalized tissue from a chronic skin wound through which subdermal or deeper tissue is exposed, and
- b) applying to healthy or healable tissue in the wound an extracellular polymeric substance solvating system comprising an aqueous solution of a metal ion sequestering agent, surfactant and buffering agent wherein the solvating system has an osmolarity greater than 900 milliosmoles of solute per liter.
A method for treating a chronic wound, which method comprises applying to healthy or healable tissue in a chronic skin wound through which subdermal or deeper tissue is exposed an extracellular polymeric substance solvating system comprising an aqueous solution of a metal ion sequestering agent, surfactant and buffering agent and having an osmolarity of about 1,000 to about 4,000 milliosmoles of solute per liter.
Dependencies are inferred from the claim text.