High oil-content emollient aerosol foam compositions
AssigneePrecision Dermatology, Inc.
InventorsRonald M. Gurge, Mark W. Trumbore, Lisa Chin, Poonam S. Hirani
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Abstract
Described herein are high oil-content emulsions and compositions for the treatment of inflammatory skin disorders. The emulsions may be formulated as aerosol compositions. The aerosol propellant may be a hydrofluoroalkane propellant. The emulsions or compositions may comprise active agents, such as corticosteroids. Also described are methods of treating inflammatory skin disorders, comprising the step of applying to an affected area of a subject in need thereof a therapeutically-effective amount of an inventive emulsion or aerosol composition.
Claims20
A method of treating an inflammatory skin disorder, comprising the step of applying to an affected area of a subject in need thereof a therapeutically-effective amount of a composition comprising:
- an emulsion, wherein the emulsion comprises
- Ceteth-20, from about 1% to about 5% by weight of the emulsion;
- cetostearyl alcohol, from about 3% to about 9% by weight of the emulsion;
- mineral oil, from about 1% to about 18% by weight of the emulsion;
- petrolatum, from about 3% to about 11% by weight of the emulsion;
- dimethicone, from about 0.5% to about 2.0% by weight of the emulsion;
- butylated hydroxytoluene, from about 0.01% to about 0.05% by weight of the emulsion;
- water, from about 27% to about 82% by weight of the emulsion;
- glycerin, from about 2.5% to about 7.5% by weight of the emulsion;
- urea, from about 0.3% to about 0.9% by weight of the emulsion;
- citric acid, from about 0.2% to about 0.6% by weight of the emulsion;
- sodium citrate, from about 0.1% to about 0.5% by weight of the emulsion;
- methylparaben, from about 0.1% to about 0.5% by weight of the emulsion;
- propylparaben, from about 0.05% to about 0.20% by weight of the emulsion;
- and
- an active agent, from about 0.002% to about 0.20% by weight of the emulsion;
- a propellant;
- and
- a purge gas.
Dependencies are inferred from the claim text.