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US 8,784,499 B2Granted
Preparation of regenerative tissue scaffolds
AssigneeLifeCell Corporation
InventorsRick Owens, Wendell Sun, Mike Liu, Yong Mao
Life of this patent
Estimating the term…
Abstract
Devices and methods for treating or repairing a tissue or organ defect or injury are provided. The devices can include tissue scaffolds produced from acellular tissue matrices and polymers, which have a stable three-dimensional shape and elicit a limited immunologic or inflammatory response.
Claims23
A tissue scaffold, comprising:
- an acellular tissue matrix (ATM) comprising a group of ATM particulates;
- and
- a polymer;
- wherein the ATM particulates are encased in the polymer to form a stable three-dimensional tissue scaffold for tissue regeneration, and the tissue scaffold has a reduced immunological or inflammatory response when implanted in a human than the polymer alone;
- and
- the polymer has been dissolved in a solvent to form a polymer solution, the ATM particulates have been submerged in and mixed with the polymer solution to form a moldable mixture, and the moldable mixture has been dried to produce a polymer scaffold completely surrounding the ATM particulates.
3 more elements
A tissue scaffold, comprising:
- an acellular tissue matrix (ATM) comprising a group of ATM particulates;
- and
- a polymer;
- wherein the ATM particulates are encased in the polymer to form a stable three-dimensional tissue scaffold for tissue regeneration, and the tissue scaffold has a reduced immunological or inflammatory response when implanted in a human than the polymer alone;
- and
- wherein the ATM particulates have been mixed with a polymer solution to form a moldable mixture, and the moldable mixture has been dried to produce the stable three-dimensional tissue scaffold.
3 more elements
Dependencies are inferred from the claim text.