Instrumented implantable stents, vascular grafts and other medical devices

A prosthetic vessel, comprising:

• a support structure, including a biocompatible material and having a structure suitable for replacement of a portion of a mammalian vessel;
• a sensor, supported by the support structure, configured to perform a measurement of a physiological parameter;
• an implantable wireless communication system, in communication with the sensor, configured to transmit information about the measurement of the physiological parameter;
• a treatment transducer, supported by the support structure, configured to deliver a treatment response;
• and
• an implantable microprocessor having an associated memory, in communication with the sensor, the implantable wireless communication systems, and the treatment transducer, the implantable microprocessor configured to control the treatment response based upon information about the measurement of the physiological parameter and a treatment protocol stored in the memory, and reprogram the memory with a new treatment protocol received through the implantable wireless communication system.