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US 8,784,408 B2Granted
LED treatment of dermatologic toxicities associated with vascular endothelial growth factor inhibitors
OwnerM. Maitland DeLand, Robert A. Weissinventors
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Abstract
The present invention relates generally to methods of preventing or treating toxicities of the skin, hair, and/or nails, which are associated with administration of one or more vascular endothelial growth factor receptor inhibitors, with light-emitting diode photomodulation treatment, either alone or in combination with other agents.
Claims22
A method of treating or preventing skin toxicity associated with administration of a vascular endothelial growth factor (VEGF) inhibitor in a subject in need thereof, said method, comprising
- directing light onto a target area on said subject, wherein said subject is administered a VEGF inhibitor therapy, said light being emitted from one or more light emitting diode (LED) sources producing at least one range of wavelengths of light,
- said light comprising about 90% of a wavelength of about 590 nm and about 10% of a wavelength of about 870 nm,
- said light further comprising pulses of light that are 250 ms in duration that are separated by 100 ms, and are repeated 100 times,
- wherein skin toxicity is in the dermis and is treated or prevented in the subject.
1 more element
Dependencies are inferred from the claim text.