Apparatus and method of dissociating ions in a multipole ion guide
AssigneeBattelle Memorial Institute
InventorsIan K. Webb, Keqi Tang, Richard D. Smith, Yehia M. Ibrahim, Gordon A. Anderson
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Abstract
A method of dissociating ions in a multipole ion guide is disclosed. A stream of charged ions is supplied to the ion guide. A main RF field is applied to the ion guide to confine the ions through the ion guide. An excitation RF field is applied to one pair of rods of the ion guide. The ions undergo dissociation when the applied excitation RF field is resonant with a secular frequency of the ions. The multipole ion guide is, but not limited to, a quadrupole, a hexapole, and an octopole.
Claims24
A method of dissociating ions in a multipole ion guide comprising:
- a. supplying a stream of charged ions to the ion guide;
- b. applying a main radio frequency (RF) field to the ion guide to confine the ions through the ion guide;
- and
- c. applying an excitation RF field of an antiphase waveform to one pair of rods of the ion guide, wherein the ions undergo dissociation when the applied excitation RF field is resonant with a secular frequency of the ions.
An apparatus for dissociating ions comprising:
- a. a multipole ion guide for receiving a stream of charged ions;
- b. a main RF field source, coupled to the ion guide, for confining the ions through the ion guide;
- c. an excitation RF field source coupled to one pair of rods of the ion guide, wherein the ions undergo dissociation when the applied excitation RF field of an antiphase waveform is resonant with a secular frequency of the ions.
A method of dissociating ions in a quadrupole ion guide comprising:
- a. supplying a stream of charged ions to the ion guide;
- b. applying a main radio frequency field to both pairs of rods of the ion guide to confine the ions through the ion guide;
- and
- c. applying an excitation RF field of an antiphase waveform to one pair of rods of the ion guide, wherein the ions undergo dissociation when the applied excitation RF field is resonant with a secular frequency of the ions, and wherein dissociated ions are left intact and not excited.
An apparatus for dissociating ions comprising:
- a. a quadrupole ion guide for receiving a stream of charged ions;
- b. a main RF field source, coupled to both pairs of rods of the ion guide, for confining the ions through the ion guide;
- c. an excitation RF field source coupled to one pair of rods of the ion guide;
- and
- d. a transformer with a primary winding coupled to the excitation RF field source and a secondary winding coupled to the main RF field source, wherein the ions undergo dissociation when the excitation RF field of an antiphase waveform is resonant with a secular frequency of the ions, and wherein dissociated ions are left intact and not excited.
Dependencies are inferred from the claim text.