Crystals of prasugrel hydrobromate
AssigneesShanghai Institute of Pharmaceutical Industry, Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
InventorsZhedong Yuan, Xingdong Cheng, Yulei Yang, Ling Tong, Xiong Yu, Laifang Zhang, Wenliang Zhou
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Abstract
The present application discloses crystals of 2-acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrobromate, crystal compositions and pharmaceutical compositions comprising them and their use. The crystals of prasugrel hydrobromate of the present application possess excellent stability and solubility.
Claims11
A crystal of a compound having formula II:
- wherein:
- Sol is acetic acid;
- and
- m is 1.
A pharmaceutical composition comprising a therapeutically effect amount of a crystal of a compound having formula II:
- wherein:
- Sol is acetic acid;
- and
- m is 1.
A method for preventing diseases associated with thrombus in an animal, comprising administering to the animal in need thereof a therapeutically effective amount of a crystal of a compound having formula II:
- wherein:
- Sol is acetic acid, and
- m is 1.
Dependencies are inferred from the claim text.