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US 8,772,445 B2Granted
Production and use of antitumoral cyclodepsipeptides
AssigneeHelmholtz-Zentrum Fuer Ozeanforschung Kiel (Geomar)
InventorsJohannes Imhoff, Zhiguo Yu, Gerhard Lang, Jutta Wiese, Holger Kalthoff, Stefanie Klose
Life of this patent
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Abstract
A compound having the general structure R1, R2, R3 and R4 being selected from the group consisting of a hydrogen atom (H) and a C1-C20 alkyl, and R5 being a phenyl radical.
Claims9
A compound having the general structure
- R1, R2, R3 and R4 being selected from the group consisting of a hydrogen atom (H) and a C1-C20 alkyl,
- and
- R5 being a phenyl radical.
A method for producing a compound having the general structure
- R1, R2, R3 and R4 being selected from the group consisting of a hydrogen atom (H) and a C1-C20
- alkyl,
- and
- R5 being a phenyl radical
- characterized by the following steps:
- a. cultivating a fungus of the species Scopulariopsis and
- b. isolating the compound from the culture medium and/or the fungus.
4 more elements
A method of treating pancreatic or intestinal cancer by administering a substance having the general structure
- R1, R2, R3 and R4 being selected from the group consisting of a hydrogen atom (H) and a C1-C20 alkyl,
- and
- R5 being a phenyl radical
- as an antitumor agent.
1 more element
Dependencies are inferred from the claim text.