Enhanced bimatoprost ophthalmic solution
AssigneeAllergan, Inc.
InventorsChin-Ming Chang, James N. Chang, Rhett M. Schiffman, R. Scott Jordan, Joan-En Chang-Lin
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Abstract
A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein. A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.
Claims20
A method of lowering intraocular pressure in a person with glaucoma or ocular hypertension, the method comprising administering once daily to an eye of the person a first composition comprising about 0.01% w/v bimatoprost and about 0.02% w/v benzalkonium chloride.
A method of lowering intraocular pressure in a person with glaucoma or elevated intraocular pressure, the method comprising administering at least once daily to an eye of the person a first composition comprising 0.01% w/v bimatoprost and 0.02% w/v benzalkonium chloride and having a pH of about 7.3, wherein the method lowers intraocular pressure and results in less hyperemia as compared to the once daily administration of a second composition comprising 0.03% w/v bimatoprost and 0.005% w/v benzalkonium chloride.
Dependencies are inferred from the claim text.