Method of treating cancer using combination of a bifunctional alkylating agent and DNA repair inhibitors
AssigneeAcademia Sinica
InventorsTe-Chang Lee, Tsann-Long Su, Ting-Chao Chou
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Abstract
A pharmaceutical composition for treating cancer, in particular drug resistant cancer, comprising an effective amount of bifunctional alkylating agent, an effective amount of a DNA repair inhibitor, and a pharmaceutically acceptable carrier.
Claims14
A pharmaceutical composition for treating cancer comprising an effective amount of a derivative of 3a-aza-cyclopentaindene selected from the group consisting of BO-1012, an effective amount of a DNA repair inhibitor, and a pharmaceutically acceptable carrier.
A method of treating cancer suffered by a mammalian subject comprising administering to the subject an effective amount of BO-1012 and an effective amount of a DNA repair inhibitor.
A pharmaceutical composition for treating cancer comprising an effective amount of BO-1509, an effective amount of a DNA repair inhibitor, and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.