Treatment methods requiring phyto-ingredients
AssigneeEnzymotec Ltd.
InventorsAvidor Shulman, Dori Pelled, Tzafra Cohen, Orly Farkash
Life of this patent
Estimating the term…
Abstract
The invention provides methods for treatment of conditions which require phytosterol therapy without adversely affecting the bioavailability of lipophilic vitamins or lipophilic drugs. The method includes administering a mixture of phytosterol ester(s) (PS-E) and 1,3-diglyceride(s) (DAG) dissolved in an edible oil or fat. The invention also provides a method of improving weight management and a method of treating metabolic conditions that result in overweight. Dietary nutrients, food supplements and food articles containing the mixture are also provided.
Claims20
A method of increasing or maintaining bioavailability of at least one lipophilic vitamin in a patient receiving phytosterol therapy, wherein the bioavailability of said at least one lipophilic vitamin in said patient is reduced as a result of said phytosterol therapy, said method comprising administering to said patient a therapeutically-effective amount of a mixture of (1) phytosterol ester(s) and/or phytostanol ester(s) (PSE) with (2) 1,3-diglyceride(s) (DAG) dissolved or dispersed in an edible fish oil, wherein fatty acid residues of the PS-E and of the DAG correspond to fatty acid residues of fish oil.
The method of claim wherein said mixture consists of 15 wt % DAG of which more than 50% are 1,3-DAG(s) and 25 wt % total PS-E(s) dissolved or dispersed in fish oil.
A method of increasing or maintaining bioavailability of at least one lipophilic vitamin in a patient receiving phytosterol therapy, wherein the bioavailability of said at least one lipophilic vitamin in said patient is reduced as a result of said phytosterol therapy, said method comprising administering to said patient a therapeutically-effective amount of a mixture consisting of (1) phytosterol ester(s) and/or phytostanol ester(s) (PS-E) with (2) 1,3-diglyceride(s) (DAG) dissolved or dispersed in fish oil wherein tai acid residues of the PS-E and of the DAG correspond to fatty acid residues of fish oil.
Dependencies are inferred from the claim text.