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AssigneeEntrechem, S.L.
InventorsLuz Elena Núñez González, Nuria Menéndez Sánchez, Javier González Sabin, Francisco Moris Varas, Beatriz García Fernández, Maria Pérez Solares, Alfredo Fernández Braña, Maria del Carmen Méndez Fernández, José Antonio Salas Fernández
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Aureolic acid derivatives, process for obtaining them and uses thereof. This invention provides a bacterial strain that produces compound belonging to the family of aureolic acids useful in the treatment of cancer or nervous system diseases.
Compound characterized by the formula VII:
The bacterial strain Streptomyces argillaceus ΔAH-W− (pMP3*BII), characterized by having the genes mtmA, mtmH y mtmW inactivated, and also by having an additional nucleic acid comprised in plasmid pMP3*BII, which encodes for enzymes involved in the biosynthesis of the sugar D-digitoxose.
Dependencies are inferred from the claim text.