Aligned nanofibers and related methods of use
AssigneeNorthwestern University
InventorsSamuel I. Stupp, Shuming Zhang, Alvaro Mata, Megan A Greenfield
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Abstract
The present invention relates to nanofibers. In particular, the present invention provides aligned nanofiber bundle assemblies. In some embodiments, the aligned nanofiber bundle assemblies are used for tissue regeneration, controlled growth of cells, and related methods (e.g., diagnostic methods, research methods, drug screening).
Claims8
A composition comprising a bundle of a plurality of longitudinally aligned nanofibers, wherein said nanofibers comprise self-assembling peptide amphiphile molecules, wherein said self-assembling peptide amphiphile molecules comprise a hydrophobic tail, a peptide segment configured for beta-sheet formation, and a charged segment;
- wherein said self-assembling peptide amphiphile molecules interact to form aligned nanofibers;
- and wherein said bundle of aligned nanofibers comprises 15-35 nanofibers.
A bundle of longitudinally aligned nanofibers, wherein said nanofibers comprise self-assembling peptide amphiphile molecules, wherein said self-assembling peptide amphiphile molecules comprise a hydrophobic tail, a peptide segment and a charged segment;
- wherein said bundle of nanofibers comprises 15-35 nanofibers.
Dependencies are inferred from the claim text.