Methods and compositions involving nucleotide repeat disorders
AssigneeBoard of Regents, The University of Texas System
InventorsPartha Sarkar, Tetsuo Ashizawa, Weidong Xu
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Abstract
The present invention concerns the methods and compositions involving nucleic acids with long repeat sequences. In some embodiments of the invention, there are methods for generating such a nucleic acid, and in other methods, there are methods for using such a nucleic acid to screen for candidate therapeutic compounds. Furthermore the present invention relates to methods of screening for Notch inhibitors and other substances that may be used to treat muscle loss and wasting.
Claims5
A method of treating muscle loss or muscle wasting in a patient comprising administering skeletrophin to the patient, wherein skeletrophin has the amino acid sequence of SEQ ID NO:4.
Dependencies are inferred from the claim text.