Monitoring myocardial infarction and its treatment

A method of managing treatment of a subject undergoing a remodeling process initiated by administration of medication following a myocardial infarction by monitoring success of the remodeling, the method comprising the steps of:

• determining an amount of a natriuretic peptide, a cardiac troponin, and an inflammatory marker in a sample from the subject, wherein the inflammatory marker is selected from growth-differentiation factor-15 (GDF-15), C-reactive protein (CRP), and osteopontin,
• initiating a remodeling process in the subject by administering a medication selected according to the level of the natriuretic peptide, cardiac troponin, and inflammatory marker determined,
• determining a second amount of the natriuretic peptide, the cardiac troponin, and the inflammatory marker in a sample from the subject,
• calculating a difference between the amounts from the first and second determination of a natriuretic peptide, a difference between the amounts from the first and second determination of cardiac troponin, and a difference between the amounts from the first and second determination of inflammatory marker,
• assessing, from the differences obtained, the success of the remodeling process, and managing the treatment by adapting the administration of medication in accordance with the assessment.