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US 8,771,941 B2Granted
Methods of assessing the risk of reproductive failure by measuring telomere length
AssigneeDavid L. Keefe
InventorDavid L. Keefe
Life of this patent
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Abstract
The invention features a method of identifying oocytes with a risk of reproductive failure and/or aneuploidy based on a telomere length assay.
Claims2
A method of in vitro fertilization comprising:
- obtaining at least one chromosome from the polar body of a fertilized human oocyte;
- measuring telomere length of the at least one chromosome;
- selecting a fertilized human oocyte having a polar body for with the measured telomere length is 7.5 kb ±1.17 kb;
- and
- after a period of incubation, implanting the embryo resulting from the selected fertilized human oocyte in a human subject.
2 more elements
A method for optimizing the viability of a human embryo comprising:
- obtaining at least one chromosome from the polar body of a fertilized human oocyte;
- measuring telomere length of the at least one chromosome;
- selecting a fertilized human oocyte having a polar body for which the measured telomere length is 7.5 kb ±1.17 kb;
- and
- after a period of incubation, implanting the embryo resulting from the selected fertilized human oocyte in a human subject.
2 more elements
Dependencies are inferred from the claim text.