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US 8,771,756 B2Granted
Biocompatible materials for medical devices
AssigneeColorado State University Research Foundation
InventorsMelissa M. Reynolds, Benjamin P. Reynolds
Life of this patent
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Abstract
The present disclosure is directed to a method of producing nitric oxide comprising (i) providing a composition comprising a metal-organic framework, and (ii) exposing the composition to a nitric oxide-releasing compound. The disclosure also is directed to compositions, coatings, and medical devices comprising a metal-organic framework.
Claims16
A method of producing nitric oxide comprising:
- providing a composition comprising a three-dimensional metal-organic framework;
- exposing the composition to physiological fluid including a nitric-oxide-releasing compound;
- and continuously producing nitric oxide from the nitric oxide releasing compound via a catalytic reaction catalyzed by the three-dimensional metal-organic framework, wherein the metal-organic framework comprises Cu3(1,3,5-benzenetricarboxylic acid)2.
Dependencies are inferred from the claim text.