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US 8,771,700 B2Granted
Interferon antagonists, antibodies thereto and associated methods of use
AssigneeRutgers, The State University of New Jersey
InventorsSergei V. Kotenko, Geoffrey L. Smith
Life of this patent
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Abstract
Described are compositions and methods useful for modulating the immune system of a subject. Also included are diagnostic methods for monitoring an immunologic condition. In particular the invention relates to antagonists of interferon proteins and associated methods of use as well as methods to develop neutralizing antibodies against IFN antagonists to treat viral infections.
Claims7
A pharmaceutical composition comprising an isolated viral polypeptide of SEQ ID NO:1 having interferon (IFN) I and IFN III antagonist activity;
- and at least one of a pharmaceutically acceptable carrier, excipient, or adjuvant.
Dependencies are inferred from the claim text.