Modulation of UL24 interactions with protein targets and uses thereof for inhibition of herpesvirus infection
AssigneeInstitut National De La Recherche Scientifique
InventorsAngela Pearson, Luc Bertrand
Life of this patent
Estimating the term…
Abstract
Methods and uses for the treatment of herpesvirus infection based on the inhibition of the interaction between herpesvirus UL24 and non-muscle myosin type IIa (NM2a) are described.
Claims3
A method for determining whether an agent may be useful for inhibiting the interaction between herpesvirus UL24 and non-muscle myosin type IIa (NM2a), wherein said method comprises contacting the UL24 polypeptide of SEQ ID NO:2 and the NM2a polypeptide of SEQ ID NO:4 in the presence of said agent, and determining whether the interaction between said UL24 and NM2a polypeptides is inhibited in the presence of said agent, wherein inhibition of the interaction between said UL24 and NM2a polypeptides in the presence of said agent is indicative that said agent may be useful for inhibiting the interaction between UL24 and NM2a.
Dependencies are inferred from the claim text.