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US 8,771,680 B2Granted
Topical co-enzyme Q10 formulations and methods of use
AssigneeUniversity of Miami
InventorsSung Lan Hsia, Niven Rajin Narain, Jie Li, Kathryn J. Russell, Karrune V. Woan, Indushekhar Persaud
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Abstract
Topical formulations of CoQ10 reduce the rate of tumor growth in an animcal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing animals with a topical formulation of CoQ10 was shown to dramatically reduce the rate of tumor growth in the animals.
Claims13
A method of treating a cancer in a subject, comprising:
- administering to a subject in need thereof, a composition comprising 1% to 25% w/w of Coenzyme Q10;
- contacting at least one tumor cell with the composition in sufficient amounts and for a sufficient time to slow the growth of the tumor cell;
- thereby treating the cancer.
Dependencies are inferred from the claim text.