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US 8,771,194 B2Granted
Modulation and analysis of cerebral perfusion in epilepsy and other neurological disorders
AssigneeNeuroPace, Inc.
InventorsMichael S. John, Benjamin D. Pless, Brett M. Wingeier
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Abstract
A system including an implantable neurostimulator device capable of modulating cerebral blood flow to treat epilepsy and other neurological disorders. In one embodiment, the system is capable of modulating cerebral blood flow (also referred to as cerebral perfusion) in response to measurements and other observed conditions. Perfusion may be increased or decreased by systems and methods according to the invention as clinically required.
Claims17
A method for responding to a neurological disorder in a human patient comprising:
- generating, by an implantable device, a signal representative of a cerebral perfusion measurement;
- receiving and processing, by the implantable device, at predetermined times, a cerebral perfusion measurement;
- automatically identifying, by the implantable device, a condition in the signal, wherein the condition comprises a predetermined change in cerebral perfusion;
- identifying, by the implantable device, a structure in a first hemisphere, monitoring, by the implantable device, the first hemisphere for increased blood flow;
- and
- automatically performing an action, by the implantable device, wherein the action comprises generating an instruction for therapy based on the identified change in the cerebral perfusion, wherein the therapy comprises stimulating a neural structure in a second hemisphere that is contralateral to the first hemisphere.
3 more elements
Dependencies are inferred from the claim text.