Capsule camera with variable illumination of the surrounding tissue

An ingestible untethered capsule for in vivo imaging and/or treatment diseased tissue within a gastrointestinal tract of animal or human being, said capsule comprising:

• a camera including an image senor and first lens located in front of the image sensor for taking in images of the diseased tissue;
• at least one light source located laterally adjacent the camera for providing one or more light beams for illumination and optical therapeutic treatment of the diseased tissue;
• a second lens located in front of the at least one light source for focusing at least one of the light beams from the at least one light source on a focus spot along a first path in a first direction onto the diseased tissue;
• and
• a detector located in front of the at least one light source for detecting second light beams reflected from the diseased tissue in a second direction opposite the first direction along the first path;
• a beam splitter located in front of the detector and configured to focus the light beams and the reflected second light beams on the detector through an aperture;
• and
• a controller connected to the camera, the second lens, and the beam splitter and configured to correct for motion of the capsule by changing settings of the second lens to maintain the focus spot, after reconstructing the images of the diseased tissue,
• wherein the second lens is scanning the reflected light beams.