7-[4-(Benzhydrylpiperazinyl-1)butyl]-3-methylxanthine and its salts with organic or inorganic acids possessing antihistaminic and antiallergenic activity

7-[4-(benzhydrylpiperazinyl-1)butyl]-3-methylxanthine or a pharmaceutically acceptable salt or hydrate thereof, capable of producing an antihistaminic and antiallergenic effect, of formula II:

• wherein R is H and R1 is Me;
• wherein n =2;
• wherein X is H;
• and wherein Y is H and Y1 is H.

7-[4-(benzhydrylpiperazinyl-1)butyl]-3-methylxanthine oxalate, capable of producing an antihistaminic and antiallergenic effect, of formula II:

• wherein R is H and R1 is Me;
• wherein n =2;
• wherein X is H;
• wherein Y is H and Y1 is H;
• and the compound as an oxalate salt.

7-[4-(benzhydrylpiperazinyl-1)butyl]-3-methylxanthine succinate, capable of producing an antihistaminic and antiallergenic effect, of formula II:

• wherein R is H and R1 is Me;
• wherein n =2;
• wherein X is H;
• wherein Y is H and Y1 is H;
• and the compound as a succinate salt.

A method of producing a salt of 7-[4-(benzhydryl-piperazinyl-1)butyl]-3-methylxanthine of formula XI:

• where HX is an organic acid or inorganic acid, comprising:
• alkylating the 7-potassium salt of 3-methylxanthine with a four-fold molar excess of 1,4-dibromobutane to produce 7-(4-bromobutyl)-3-methylxanthine;
• reacting the 7-(4-bromobutyl)- 3-methylxanthine with 1-benzhydrylpiperazine to produce 7-[4-(4-benzhydryl-piperazinyl-1)butyl]-3-methylxanthine;
• and neutralizing the 7-[4-(4-benzhydryl-piperazinyl-1)butyl]-3-methylxanthine with the organic or inorganic acid to form the salt.