Ophthalmic compositions and methods for treating eyes
AssigneeAllergan, Inc.
InventorsJoseph G. Vehige, Peter A. Simmons, Joan-En Chang-Lin
Life of this patent
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Abstract
Ophthalmic compositions including compatible solute components and/or polyanionic components are useful in treating eyes, for example, to relieve dry eye syndrome, to protect the eyes against hypertonic insult and/or the adverse effects of cationic species on the ocular surfaces of eyes and/or to facilitate recovery from eye surgery.
Claims16
A method of treating dry eye, wherein the method comprises administering a topical ophthalmic composition comprising a therapeutically effective amount of each of:
- an aqueous carrier;
- erythritol, and its isomers thereof;
- carnitine, its isomers or suitable salts thereof;
- glycerin;
- and
- an ionically charged polymeric material selected from the group consisting of carboxymethyl cellulose and mixtures of carboxymethyl cellulose compounds.
A method for treating dry eye, wherein the method comprises dispensing to the ocular surface a composition comprising a therapeutically effective amount of each of:
- erythritol, and its isomers thereof;
- carnitine, its isomers or suitable salts thereof;
- glycerin;
- carboxymethylcellulose;
- and
- water.
A method for the treatment of dry eye, the method comprising administering to an eye needing treatment a composition comprising a therapeutically effective amount of each of:
- carnitine, or a stereoisomer or a salt thereof;
- erythritol, or a stereoisomer thereof;
- glycerin, or a stereoisomer thereof;
- at least one anionic cellulose derivative;
- a tonicity adjusting component that is not erythritol;
- and
- water.
Dependencies are inferred from the claim text.