Soluble guanylate cyclase activators

A compound of the formula I

• wherein:
• A is a 5- or 6-membered aryl, heteroaryl or heterocyclyl group;
• B is a 5-7 membered heterocyclyl group containing one nitrogen, wherein one carbon of the heterocyclyl group is optionally substituted with an oxo group, or B is a 5-membered heteroaryl group containing at least 2 nitrogens;
• R1 and R2 are independently selected from H, C1-4alkyl, C3-6cycloalkyl, tetrahydropyranyl, —CF3, —CH2CF3 and —CH2CH2CO2H;
• R3 is selected from H and —CH3;
• R4 is selected from H, C1-6alkyl, C3-7cycloalkyl, —C(O)C1-6alkyl, —CH2CF3, —SO2C1-6alkyl, —SO2(CH2)1-3CO2H, —CO2C1-4alkyl, heterocyclyl, aryl, heteroaryl, —(C0-2alkyl)heterocyclyl, —(C1-2alkyl)aryl and —(C1-2alkyl)heteroaryl,
• wherein said heterocyclyl is selected from tetrahydrofuranyl, azetidinyl, pyrrolidinyl, pyranyl, tetrahydropyranyl, dioxanyl, thiomorpholinyl, 1,1-dioxo-1λ6-thiomorpholinyl, morpholinyl, piperidinyl, piperazinyl, and azepinyl, and
• said heterocyclyl, cycloalkyl, aryl and heteroaryl are optionally substituted with one to two groups independently selected from C1-3alkyl, —CF3, and halogen,
• or R4 is optionally not present when B is a heteroaryl group;
• R5 is selected from H, —C1-3alkyl, —OCH3, —CF3, —CN and Cl;
• and
• R6 is selected from H and CH3;
• provided that R5 and R6 are not both H;
• or a salt thereof.