Method for improving heat stability of composition containing water-soluble coenzyme-bound glucose dehydrogenase (GDH)
AssigneeToyo Boseki Kabushiki Kaisha
InventorMasao Kitabayashi
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Abstract
The invention relates to a method for improving the heat stability of glucose dehydrogenase (GDH). The invention provides a method for preparing a glucose sensor with soluble flavin-bound GDH by providing a composition comprising soluble flavin-bound GDH at an acidic pH and heat drying the composition onto a glucose sensor.
Claims6
A method for preparing a glucose sensor with soluble flavin-bound glucose dehydrogenase, which method comprises (a) providing a composition comprising soluble flavin-bound glucose dehydrogenase at a pH in the range of 3.14 to 6.97 and (b) drying the composition onto a surface of a glucose sensor, wherein the soluble flavin-bound glucose dehydrogenase is from an Aspergillus microorganism.
A method for preparing a glucose sensor with soluble flavin-bound glucose dehydrogenase, which method comprises (a) providing a composition comprising soluble flavin-bound glucose dehydrogenase at a pH in the range of 4.20 to 6.60 and (b) drying the composition onto a surface of a glucose sensor, wherein the soluble flavin-bound glucose dehydrogenase is from an Aspergillus microorganism.
Dependencies are inferred from the claim text.