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AssigneeDimerix Bioscience Pty Ltd.
InventorsKevin Donald George Pfleger, Ruth Marie Seeber, Heng Boon See, Karin Ann Eidne
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A system for the detection of molecular associations, the system comprising: i) a first agent, comprising a first interacting group coupled to a first reporter component; ii) a second agent, comprising a second interacting group coupled to a second reporter component; iii) a third agent, comprising a third interacting group; iv) a modulator; and v) a detector; wherein proximity of the first and second reporter components generates a signal capable of detection by the detector; and wherein the modulator modulates the association of the second interacting group with the third interacting group; such that monitoring the signal generated by proximity of the first and second reporter components by the detector constitutes monitoring the association of the first and third agents.
A kit for determining whether and/or the extent to which a test compound interacts with a second receptor when the second receptor is associated with a first receptor, wherein the first receptor is different from the second receptor, the kit comprising:
A kit for screening a test compound for selective activity against a heterodimer of a first receptor and a second receptor, the kit comprising:
Dependencies are inferred from the claim text.