EGFR polymorphisms predict gender-related treatment
AssigneeUniversity of Southern California
InventorHeinz-Josef Lenz
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Abstract
The invention provides compositions and methods for identifying a gender-specific cancer patient suitable for treatment with various treatment regimens available to cancer patients. After determining if a patient is suitable for therapy, the invention also provides methods for treating these patients.
Claims12
A method for identifying and treating a female colon cancer patient suitable for a pyrimidine antimetabolite based therapy, comprising screening a cell or tissue sample isolated from the patient for the EGFR polymorphism of R497K and administering an effective amount of the therapy to a patient having the genotype of Arg/Arg for R497K.
Dependencies are inferred from the claim text.