Hydroxyalkylcellulose microparticles
AssigneeNippon Soda Co., Ltd.
InventorsHirofumi Takeuchi, Satoru Abe, Takeshi Shimotori, Gentaro Nemoto
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AssigneeNippon Soda Co., Ltd.
InventorsHirofumi Takeuchi, Satoru Abe, Takeshi Shimotori, Gentaro Nemoto
Estimating the term…
Provided is a method of producing hydroxyalkylcellulose microparticles, the method including generating a pulse shock wave, and supplying a hydroxyalkylcellulose aqueous solution to the pulse shock wave generation region, thereby crushing and drying the hydroxyalkylcellulose aqueous solution. According to the production method, hydroxyalkylcellulose microparticles having a volume-average particle size of at least 0.1 μm but less than 15 μm are obtained. By mixing the hydroxyalkylcellulose microparticles with a principal agent and subjecting the resulting mixture to a tablet compression, a solid preparation having excellent tensile strength and disintegration properties can be obtained.
Hydroxyalkylcellulose microparticles, having a volume-average particle size of at least 0.1 μm but less than 15 μm, wherein a 2% aqueous solution of said microparticles has a viscosity at 20° C. that is within a range from 2.0 to 20.0 mPa·s.
Dependencies are inferred from the claim text.