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US 8,541,743 B2Granted
Apparatus and method for detecting and quantifying analytes in solution
AssigneeRoc8Sci Co.
InventorFrank Thomas Hartley
Life of this patent
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Abstract
A method for identifying and quantifying one or more analytes included in a sample comprising a background solvent is disclosed. The present invention locates a sample fluid at a sample region by virtue of a sample holder that comprises work-hardened silver halide. The sample fluid at the sample region is then spectrally characterized via a mid-infrared spectrometer.
Claims30
An apparatus comprising:
- (1) a spectrometer comprising;
- (i) a source operable for providing mid-infrared radiation to a sample region;
- (ii) a wavelength discriminator operable for receiving a composite light signal from the sample region and spatially dispersing the composite light signal as a plurality of wavelength signals;
- and
- (iii) a plurality of detectors, each of the plurality of detectors operable for generating one of a plurality of first electrical signals based on one of the plurality of wavelength signals;
- and
- (2) a sample holder, the sample holder being operable for locating a sample fluid at the sample region, the sample holder being dimensioned and arranged to enable the sample fluid to (a) receive mid-infrared radiation such that at least a portion of the mid-infrared radiation transits the sample fluid and (b) provide the composite light signal.
4 more elements
An apparatus comprising:
- (1) a spectrometer comprising;
- (i) a source operable for providing mid-infrared radiation;
- (ii) a wavelength discriminator operable for spatially dispersing a composite light signal into a plurality of wavelength signals;
- and
- (iii) a plurality of detectors, each of the plurality of detectors operable for generating one of a plurality of first electrical signals based on one of the plurality of wavelength signals;
- and
- (2) a sample holder that includes a sample cell that comprises work-hardened silver halide, the sample holder operable for locating a sample fluid such that the sample fluid (a) receives mid-infrared radiation from the source such that at least a portion of the mid-infrared radiation transits the sample fluid and (b) provides the composite light signal to the wavelength discriminator such that the composite light signal includes the mid-infrared radiation and spectral information based on the sample fluid.
4 more elements
An apparatus comprising:
- (1) a spectrometer comprising;
- (i) a source operable for providing mid-infrared radiation;
- (ii) a first optical fiber operable for conveying mid-infrared radiation from the source to a sample region, the first optical fiber comprising silver halide;
- (iii) a second optical fiber operable for conveying a composite light signal comprising mid-infrared radiation from the sample region to a wavelength discriminator, the second optical fiber comprising silver halide;
- (iv) the wavelength discriminator, the wavelength discriminator being operable for receiving the composite light signal and spatially dispersing it as a plurality of wavelength signals;
- and
- (v) a plurality of detectors, each of the plurality of detectors operable for generating one of a plurality of first electrical signals based on one of the plurality of wavelength signals;
- and
- (2) a sample holder, the sample holder being operable for locating a sample fluid at the sample region, the sample holder being dimensioned and arranged to enable the sample fluid to (a) receive mid-infrared radiation such that at least a portion of the mid-infrared radiation transits the sample fluid and (b) provide the composite light signal.
6 more elements
A method comprising:
- locating a sample fluid in a sample region, the sample fluid including a first chemical constituent and a background solvent, the sample fluid being located by a sample holder that enables mid-infrared radiation to transit the sample fluid and enables the sample fluid to provide a composite light signal;
- passing mid-infrared radiation through the sample fluid;
- providing the composite light signal such that it includes spectral information based on each of a first chemical constituent and the background solvent;
- distributing the first composite light signal into a plurality of wavelength signals;
- and
- providing a first electrical signal based on the plurality of wavelength signals.
3 more elements
Dependencies are inferred from the claim text.