Back to results
US 8,541,670 B2Granted
Compositions and methods for inhibiting tumor cell growth
OwnerEffat Emamianinventor
Life of this patent
Estimating the term…
Abstract
The present invention relates to compositions and methods for inhibiting the activity of an enzyme, for example, Protein Kinase B, p70S6K and/or Abl using the catalytic subunit of Protein Kinase A (PKAc), or at least one PKAc fragment or variant PKAc fragment thereof. In this regard, methods for preventing or treating cancer or a neurodegenerative disease or disorder are also provided.
Claims8
A composition comprising one or more peptide(s), wherein the peptide(s) is a PKAc fragment or variant thereof selected from the group consisting of;
- (a) the peptide of SEQ ID NO:
- 60;
- and
- (b) a peptide variant that has at least 40% identity with SEQ ID NO:
- 60 and inhibits human AKT1.
2 more elements
Dependencies are inferred from the claim text.