N-acyl cyclic amine derivative or pharmaceutically acceptable salt thereof

A compound of the following formula (1):

• wherein Ar1 and Ar2 are each independently optionally substituted C6-10 aryl or optionally substituted heteroaryl;
• V is CR3, in which R3 is hydrogen, hydroxyl, halogen, cyano, or optionally substituted C1-6 alkyl;
• W1 is a single bond, oxygen, sulfur, —C(O)— or —NR2—, in which R2 is hydrogen or optionally substituted C1-6 alkyl,
• piperidine ring in case that V is CR3 may be each independently optionally substituted by one or more and same or different groups selected from the group consisting of hydroxyl, halogen, cyano, C1-6 alkyl and C1-6 alkoxy on any substituent positions;
• W2 is optionally substituted ethylene;
• W3 is a single bond, oxygen, sulfur, —NH—, optionally substituted methylene, optionally substituted ethylene, or —CR4═CR5—, in which R4 and R5 are each independently hydrogen, halogen or optionally substituted C1-6 alkyl;
• Ring Q is a group of the following formula (a):
• in which n is 0;
• m is 0, 1 or 2;
• k is 1, 2 or 3;
• Z is a single bond, methylene, oxygen, sulfur, —S(O)—, —S(O)2— or —NR21—, in which R21 is hydrogen or optionally substituted C1-6 alkyl;
• R1a, R1b and R1c are each, same or different, hydrogen, hydroxyl, halogen, cyano, carboxyl, optionally substituted amino, optionally substituted C1-6 alkyl, optionally substituted C3-7 cycloalkyl, optionally substituted C3-7 cycloalkyl-C1-4 alkyl, optionally substituted C7-14 aralkyl, optionally substituted heteroaryl-C1-4 alkyl, optionally substituted saturated heterocyclic C1-4 alkyl, optionally substituted C6-10 aryl, optionally substituted heteroaryl, optionally substituted saturated heterocycle, optionally substituted C1-6 alkoxy, optionally substituted C3-7 cycloalkoxy, optionally substituted C6-10 aryloxy, optionally substituted heteroaryloxy, optionally substituted saturated heterocyclic oxy, optionally substituted C7-14 aralkyloxy, optionally substituted C1-6 alkylcarbonylamino, optionally substituted C3-7 cycloalkylcarbonylamino, optionally substituted C6-10 arylcarbonylamino, optionally substituted saturated heterocyclic carbonylamino, optionally substituted heteroarylcarbonylamino, optionally substituted C1-6 alkylcarbonyloxy, optionally substituted aminocarbonyloxy, optionally substituted C1-6 alkoxycarbonylamino, optionally substituted C3-7 cycloalkoxycarbonylamino, optionally substituted saturated heterocyclic oxycarbonylamino, optionally substituted aminocarbonylamino, optionally substituted aminosulfonylamino, optionally substituted C1-6 alkylsulfonylamino, optionally substituted C3-7 cycloalkylsulfonylamino, optionally substituted C6-10 arylsulfonylamino, optionally substituted saturated heterocyclic sulfonylamino, or optionally substituted heteroarylsulfonylamino,
• alternatively, R1a and R1b may combine each other together with the carbon atom to which they bind to form C3-7 cycloalkyl ring, or saturated heterocycle, in which the C3-7 cycloalkyl ring and the saturated heterocycle may be optionally substituted by one or more and same or different groups selected from the group consisting of hydroxyl, halogen, cyano, C1-6 alkyl, C1-6 alkoxy, C6-10 aryl, heteroaryl and 4- to 7-membered saturated heterocycle;
• or a pharmaceutically acceptable salt thereof.