Substituted benzo-pyrido-triazolo-diazepine compounds

A compound of Formula I:

• or a pharmaceutically acceptable salt or ester thereof, wherein:
• X1 is CRX1 or N;
• X2 is CRX2 or N;
• RX1, RX2, RP1 and RP2 are each independently H, hydroxyl, halogen, cyano, nitro, amino, unsubstituted or substituted C1-C6 alkyl, unsubstituted or substituted C1-C6 alkoxy, unsubstituted or substituted C6-C10 aryl, unsubstituted or substituted heteroaryl comprising one or two 5- or 6-member rings and 1- 4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle or unsubstituted or substituted heterocycle comprising one or two 5- or 6-member rings and 1- 4 heteroatoms selected from N, O and S;
• Q is (CH2)z or a bond;
• z is 1, 2, 3, 4, 5 or 6;
• T is hydroxyl, halogen, cyano, nitro, amino, unsubstituted or substituted C6-C10 aryl or unsubstituted or substituted C3-C10 carbocycle;
• RN is H or unsubstituted or substituted C1-C6 alkyl;
• m is 0, 1, 2, 3 or 4;
• and
• each R1 is independently hydroxyl, halogen, cyano, nitro, amino, unsubstituted or substituted C1-C6 alkyl, unsubstituted or substituted C6-C10 aryl, unsubstituted or substituted heteroaryl comprising one or two 5- or 6-member rings and 1- 4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle or unsubstituted or substituted heterocycle comprising one or two 5- or 6-member rings and 1-4heteroatoms selected from N, O and S.