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US 8,541,377 B2Granted
Optimized dengue virus entry inhibitory peptide (DN81)
AssigneeFlorida Gulf Coast University
InventorsScott F. Michael, Sharon Isern, Robert Garry, Ram Samudrala, Joshua Costin, Ekachai Jenwitheesuk
Life of this patent
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Abstract
The invention relates peptide entry inhibitors and methods of determining such inhibitors that are bindable to regions of viruses having class II E proteins, such as the dengue virus E protein, as candidates for in vivo anti-viral compounds.
Claims13
A synthetic peptide comprising:
- an amino acid sequence presented as SEQ ID NO:
- 1.
A method of treating dengue virus infection in a subject comprising the steps of:
- administering a therapeutically effective amount of the peptide comprising the amino acid sequence presented as SEQ ID NO:
- 1 to a subject in need thereof.
Dependencies are inferred from the claim text.