Plasma anti-diabetic NUCB2 peptide (pladin) and uses thereof
AssigneeLanding Biotech, Inc.
InventorJian-ning Liu
Life of this patent
Estimating the term…
Abstract
The present invention provides pladin (plasma anti-diabetic nucb2 peptide) polypeptide and functional equivalent thereof that are useful for treating diabetes. The present invention provides a method of treating diabetes by administering to a subject nesfatin-1, pladin, or a functional equivalent thereof. The present invention also provides a method of treating diabetes by administering to subject plasmin inhibitors.
Claims9
A method of lowering blood glucose in a subject having diabetes comprising the step of administering to said subject a composition comprising an effective amount of an insulin helper pladin (plasma anti-diabetic nucb2 peptide) consisting of the amino acid sequence of SEQ ID NO:
- 23.
A recombinant pladin (plasma anti-diabetic nucb2 peptide) consisting of the amino acid sequence of SEQ ID NO:
- 23.
A recombinant pladin (plasma anti-diabetic nucb2 peptide) consisting of the amino acid sequence of SEQ ID NO:
- 23, wherein the pladin has a mutation at Arg13 or Lys28.
Dependencies are inferred from the claim text.