US 8,541,201 B2Granted

Thrombopoietic compounds

AssigneeAmgen Inc.

InventorsHosung Min, Kenneth W. Walker, Colin V. Gegg, Francesco Galimi, Jeonghoon Sun, Mei-Mei Tsai

Life of this patent

Estimating the term…

Abstract

The invention relates to the field of compounds, especially peptides or polypeptides, that have thrombopoietic activity. The peptides and polypeptides of the invention may be used to increase platelets or platelet precursors (e.g., megakaryocytes) in a mammal.

Claims4

Dependent claims

An isolated polynucleotide that encodes a compound that binds to an mpl receptor, wherein said compound is selected from the group consisting of SEQ ID NOS:

353-422.

Dependencies are inferred from the claim text.

Facts

Application: 13/186,443Filed 19 Jul 2011 · division
Priority: 19 Jun 2006
Published: US 2011/0275122 A110 Nov 2011
Granted: 24 Sep 2013
Term ends: Not estimatedThe source records don’t support an estimate.

Classification10 codes

C07K 14/524
Cytokines; Lymphokines; Interferons: thrombopoietin, i.e. C-MPL ligand
A61K 38/17
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from animals; from humans
A61P 7/02
Drugs for disorders of the blood or the extracellular fluid: antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
C07K 7/06
Linear peptides containing only normal peptide links: having 5 to 11 amino acids

Family

Application60/814,990Us provisional application · filed 19 Jun 2006
Application60/844,301Us provisional application · filed 13 Sep 2006
Application11/820,463Parent of this division · filed 18 Jun 2007
US 2011/0275122 A1Pre-grant publication · published 10 Nov 2011
US 7,981,425 B2Parent of this division
US 2008/0070840 A1Published application
US 8,541,201 B2This patent

From the US filing history. Foreign family members aren’t listed.

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