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AssigneeThe Institute for Ethnomedicine
InventorsPaul Alan Cox, Sandra Banack, Susan Murch
Estimating the term…
Methods for screening for neurological disorders are disclosed. Specifically, methods are disclosed for screening for neurological disorders in a subject by analyzing a tissue sample obtained from the subject for the presence of elevated levels of neurotoxic amino acids or neurotoxic derivatives thereof associated with neurological disorders. In particular, methods are disclosed for diagnosing a neurological disorder in a subject, or predicting the likelihood of developing a neurological disorder in a subject, by determining the levels of β-N-methylamino-L-alanine (BMAA) in a tissue sample obtained from the subject. Methods for screening for environmental factors associated with neurological disorders are disclosed. Methods for inhibiting, treating or preventing neurological disorders are disclosed.
A method of screening a subject having or at risk of having Parkinson's Disease (PD) comprising, obtaining a tissue sample from the subject and analyzing the sample to determine the amount of protein-bound β-N-methylamino-L-alanine (BMAA), wherein the presence of BMAA in the sample indicates the subject has or is at risk of having PD.
Dependencies are inferred from the claim text.