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US 8,541,026 B2Granted
Sustained release formulations of opioid and nonopioid analgesics
AssigneeAbbVie Inc.
InventorsYihong Qiu, Cheri E Klein
Life of this patent
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Abstract
The present invention relates to SRSR solid dosage forms for administering pharmaceutical agents, particularly Hydrocodone and acetaminophen, methods for preparing the dosage forms, and methods for providing therapeutic agents to patients in need of treatment.
Claims23
A pharmaceutical composition comprising at least two sustained release subunits:
- a first sustained release subunit that comprises acetaminophen and hydrocodone or an equivalent amount of another acceptable salt or free base of hydrocodone thereof;
- a second sustained release subunit that comprises acetaminophen and hydrocodone or an equivalent amount of another acceptable salt or free base of hydrocodone thereof;
- wherein each of the sustained release subunits are in a monoeximic dosage form selected from the group consisting of an osmotic system and a matrix system,
- wherein each monoexemic osmotic system contains only one membrane to control the rate of drug release, and
- wherein the sustained release subunits release the drugs contained therein over a period of longer than two hours.
2 more elements
Dependencies are inferred from the claim text.