Phospholipid ether analogs as agents for detecting and locating cancer, and methods thereof
AssigneeCellectar, Inc.
InventorsJamey Weichert, Marc Longino, Anatoly Pinchuk
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Abstract
The present invention provides methods for treating, detecting and locating recurrence of cancer, radiation and chemo insensitive cancer or metastasis of cancer selected from the group consisting of Lung cancer, Adrenal cancer, Melanoma, Colon cancer, Colorectal cancer, Ovarian cancer, Prostate cancer, Liver cancer, Subcutaneous cancer, Squamous cell cancer, Intestinal cancer, Hepatocellular carcinoma, Retinoblastoma, Cervical cancer, Glioma, Breast cancer and Pancreatic cancer in subject using phospholipid ether analogs.
Claims5
A method for detecting and locating a cancer in vivo, the method comprising the steps of:
- administering 124I-labeled 18-(p-Iodophenyl)octadecyl phosphocholine to the human subject;
- and
- determining whether an organ suspected of having the cancer in the subject retains a higher level of 124I-labeled 18-(p-Iodophenyl)octadecyl phosphocholine than surrounding region(s), wherein a higher retention region indicates detection and location of the cancer, wherein the detection is carried out by PET scanning.
Dependencies are inferred from the claim text.